3 Most Effective Workout Splits for Building Muscle Mass in 2025

Building muscle mass efficiently requires a well-structured workout programme tailored to individual goals, experience levels, and recovery capacities. In 2025, the science of hypertrophy continues to underscore the importance of optimising workout splits to maximise gains.

This article explores three of the most effective workout splits for building muscle, backed by scientific evidence, and explains how to implement them successfully.

Full-Body Workout Split

What is the Full-Body Workout Split?

The full-body workout split involves training all major muscle groups in a single session, typically performed three times a week. Each workout includes compound lifts, such as squats, deadlifts, and bench presses, which engage multiple muscle groups simultaneously.

Why is it Effective?

  1. High Training Frequency: Research indicates that stimulating each muscle group two to three times per week promotes greater hypertrophy compared to lower frequencies (Schoenfeld et al., 2016).
  2. Time Efficiency: Full-body workouts minimise the total number of weekly gym sessions while maintaining a high volume of work.
  3. Enhanced Recovery: With rest days between sessions, muscles have sufficient time to recover, enabling progressive overload.

Example Full-Body Workout Plan

Day 1: Squats, Bench Press, Pull-Ups, Overhead Press, Plank Day 2: Rest Day 3: Deadlifts, Incline Dumbbell Press, Barbell Rows, Lateral Raises, Hanging Leg Raises Day 4: Rest Day 5: Front Squats, Weighted Dips, Chin-Ups, Bulgarian Split Squats, Russian Twists

Scientific Backing

A 2019 meta-analysis by Grgic et al. confirmed that training frequency significantly impacts muscle growth, especially when total weekly volume is equated.

Upper/Lower Body Split

What is the Upper/Lower Body Split?

This split alternates between upper and lower body training days, usually performed four times a week. It allows for a higher training volume per muscle group in each session.

Why is it Effective?

  1. Volume and Intensity: By focusing on either the upper or lower body in each session, lifters can dedicate more energy to each muscle group, improving workout quality.
  2. Flexibility: This split suits intermediate to advanced lifters as it balances volume, intensity, and recovery.
  3. Progressive Overload: The split enables consistent progression in both compound and isolation exercises.

Example Upper/Lower Workout Plan

Day 1: Upper Body – Bench Press, Pull-Ups, Overhead Dumbbell Press, Barbell Rows, Bicep Curls Day 2: Lower Body – Squats, Deadlifts, Walking Lunges, Hamstring Curls, Calf Raises Day 3: Rest Day 4: Upper Body – Incline Bench Press, Chin-Ups, Arnold Press, T-Bar Rows, Tricep Pushdowns Day 5: Lower Body – Front Squats, Romanian Deadlifts, Step-Ups, Glute Bridges, Seated Calf Raises

Scientific Backing

A study by Wirth et al. (2021) highlighted that higher weekly training volumes achieved through splits like this are correlated with enhanced muscle hypertrophy and strength gains.

Push/Pull/Legs (PPL) Split

What is the Push/Pull/Legs Split?

The PPL split divides workouts into push (chest, shoulders, triceps), pull (back, biceps), and legs (quadriceps, hamstrings, calves) sessions. It’s commonly performed over a six-day weekly schedule, with one rest day.

Why is it Effective?

  1. Specialisation: This split allows lifters to focus on specific movement patterns, optimising muscle recruitment.
  2. Volume Distribution: Muscle groups are given adequate stimulus without overtraining, as they’re trained once or twice a week.
  3. Adaptability: PPL suits both hypertrophy and strength training by adjusting rep ranges and exercise selection.

Example Push/Pull/Legs Workout Plan

Day 1: Push – Bench Press, Overhead Press, Dips, Tricep Extensions, Lateral Raises Day 2: Pull – Deadlifts, Pull-Ups, Barbell Rows, Bicep Curls, Face Pulls Day 3: Legs – Squats, Romanian Deadlifts, Leg Press, Calf Raises, Hanging Leg Raises Day 4: Rest Day 5: Repeat Days 1-3

Scientific Backing

A study by Schoenfeld and colleagues (2019) showed that distributing training volume across multiple weekly sessions enhances hypertrophy compared to once-weekly high-volume sessions. The PPL split aligns well with this principle.

Key Considerations for Effective Muscle Growth

Progressive Overload

Regardless of the split, progressively increasing resistance over time is critical for hypertrophy. A systematic review by Dankel et al. (2017) affirmed the importance of load progression in muscle building.

Nutrition and Recovery

Muscle growth is not just about training; proper nutrition and recovery play pivotal roles. Consuming adequate protein (1.6-2.2g/kg body weight daily) and ensuring 7-9 hours of quality sleep are essential (Morton et al., 2018).

Individualisation

Tailor the split to your experience level, lifestyle, and recovery capacity. Beginners may thrive on a full-body split, while intermediate and advanced lifters often benefit more from Upper/Lower or PPL splits.

Conclusion

Choosing the right workout split is integral to achieving optimal muscle growth. The Full-Body, Upper/Lower Body, and Push/Pull/Legs splits offer scientifically supported frameworks for hypertrophy, each catering to different needs and levels of experience. To maximise results, incorporate progressive overload, prioritise recovery, and adhere to evidence-based nutrition strategies.

Key Takeaways Details
Full-Body Split Ideal for beginners or those with limited training time. High frequency, compound lifts emphasised.
Upper/Lower Split Suitable for intermediates, offering balanced volume and recovery. Focus on specific muscle groups per session.
Push/Pull/Legs Best for advanced lifters. Specialised sessions, high weekly training volume.
Recovery and Nutrition Essential for all splits. Ensure progressive overload, proper protein intake, and sufficient sleep.

References

Dankel, S.J., et al., 2017. Resistance training induced increases in muscle size are not limited by the volume of exercise performed per muscle group. European Journal of Applied Physiology, 117(7), pp.1359-1367.

Grgic, J., et al., 2019. Frequency of resistance training for muscle strength and hypertrophy: a systematic review and meta-analysis. Sports Medicine, 49(9), pp.1443-1457.

Morton, R.W., et al., 2018. Protein intake to maximise whole-body anabolism during postexercise recovery: an update. The Journal of Nutrition, 148(12), pp.1901-1910.

Schoenfeld, B.J., et al., 2016. Effects of resistance training frequency on measures of muscle hypertrophy: a systematic review and meta-analysis. Sports Medicine, 46(11), pp.1689-1697.

Wirth, K., et al., 2021. Training volume and intensity distribution in resistance training. Strength & Conditioning Journal, 43(2), pp.33-42.

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